HCSGD entry for PHYH
1. General information
| Official gene symbol | PHYH |
|---|---|
| Entrez ID | 5264 |
| Gene full name | phytanoyl-CoA 2-hydroxylase |
| Other gene symbols | LN1 LNAP1 PAHX PHYH1 RD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001561 | Fatty acid alpha-oxidation | IDA IEA TAS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005777 | Peroxisome | IDA IEA | cellular_component |
| GO:0005782 | Peroxisomal matrix | TAS | cellular_component |
| GO:0006720 | Isoprenoid metabolic process | IDA | biological_process |
| GO:0009055 | Electron carrier activity | TAS | molecular_function |
| GO:0031418 | L-ascorbic acid binding | IEA | molecular_function |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048037 | Cofactor binding | IDA | molecular_function |
| GO:0048244 | Phytanoyl-CoA dioxygenase activity | IDA IEA TAS | molecular_function |
| GO:0097089 | Methyl-branched fatty acid metabolic process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0522768322 | 0.4586872041 | 0.5002105780 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.0120449609 |
| GSE13712_SHEAR | Down | -0.6592082369 |
| GSE13712_STATIC | Down | -0.5988551858 |
| GSE19018 | Up | 0.7452242926 |
| GSE19899_A1 | Down | -0.2066120174 |
| GSE19899_A2 | Up | 0.4076626029 |
| PubMed_21979375_A1 | Up | 0.1984794324 |
| PubMed_21979375_A2 | Up | 0.6147866426 |
| GSE35957 | Down | -0.3150069340 |
| GSE36640 | Down | -0.1085198482 |
| GSE54402 | Down | -0.0554842885 |
| GSE9593 | Up | 0.2125943080 |
| GSE43922 | Down | -0.0077989462 |
| GSE24585 | Up | 1.0106331081 |
| GSE37065 | Up | 0.1652625686 |
| GSE28863_A1 | Up | 0.0854694133 |
| GSE28863_A2 | Up | 0.2943795204 |
| GSE28863_A3 | Down | -0.1161205039 |
| GSE28863_A4 | Down | -0.0606769945 |
| GSE48662 | Down | -0.1920465359 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Vitamin C | DB00126 | NUTR00001 | APRD00084 | EXPT00568 | DB09541 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050505 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
