HCSGD entry for PHF1
1. General information
| Official gene symbol | PHF1 |
|---|---|
| Entrez ID | 5252 |
| Gene full name | PHD finger protein 1 |
| Other gene symbols | MTF2L2 PCL1 PHF2 TDRD19C hPHF1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | TAS | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005815 | Microtubule organizing center | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006974 | Cellular response to DNA damage stimulus | IDA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016568 | Chromatin modification | IEA | biological_process |
| GO:0035064 | Methylated histone residue binding | IDA IEA | molecular_function |
| GO:0035098 | ESC/E(Z) complex | IDA | cellular_component |
| GO:0035861 | Site of double-strand break | IDA | cellular_component |
| GO:0061086 | Negative regulation of histone H3-K27 methylation | IMP | biological_process |
| GO:0061087 | Positive regulation of histone H3-K27 methylation | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1280799628 | 0.7145194635 | 0.7276478955 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4161198150 |
| GSE13712_SHEAR | Down | -0.1663859572 |
| GSE13712_STATIC | Down | -0.0419016965 |
| GSE19018 | Up | 0.4486243858 |
| GSE19899_A1 | Down | -0.1883927676 |
| GSE19899_A2 | Down | -0.0238546727 |
| PubMed_21979375_A1 | Up | 0.2206552525 |
| PubMed_21979375_A2 | Down | -0.1697970255 |
| GSE35957 | Down | -0.1967596470 |
| GSE36640 | Up | 0.2491647367 |
| GSE54402 | Up | 0.2723136527 |
| GSE9593 | Up | 0.4954227343 |
| GSE43922 | Up | 0.0321538718 |
| GSE24585 | Up | 0.6277204745 |
| GSE37065 | Up | 0.1991110381 |
| GSE28863_A1 | Down | -0.3060815949 |
| GSE28863_A2 | Up | 0.1940151821 |
| GSE28863_A3 | Up | 0.2214201250 |
| GSE28863_A4 | Down | -0.3511658322 |
| GSE48662 | Up | 0.1674134647 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
