HCSGD entry for SLC25A3
1. General information
| Official gene symbol | SLC25A3 |
|---|---|
| Entrez ID | 5250 |
| Gene full name | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 |
| Other gene symbols | PHC PTP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006091 | Generation of precursor metabolites and energy | TAS | biological_process |
| GO:0006810 | Transport | IEA TAS | biological_process |
| GO:0006820 | Anion transport | TAS | biological_process |
| GO:0015293 | Symporter activity | IEA | molecular_function |
| GO:0015320 | Phosphate ion carrier activity | TAS | molecular_function |
| GO:0015698 | Inorganic anion transport | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0032403 | Protein complex binding | IDA | molecular_function |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0035435 | Phosphate ion transmembrane transport | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8477027848 | 0.0564018806 | 0.9999902473 | 0.4463920697 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2503048317 |
| GSE13712_SHEAR | Down | -0.3400837536 |
| GSE13712_STATIC | Down | -0.3199361009 |
| GSE19018 | Down | -0.6050103651 |
| GSE19899_A1 | Down | -0.1252934718 |
| GSE19899_A2 | Up | 0.3119687729 |
| PubMed_21979375_A1 | Up | 0.2430231109 |
| PubMed_21979375_A2 | Down | -0.0809884466 |
| GSE35957 | Up | 0.3215658814 |
| GSE36640 | Up | 0.3100565372 |
| GSE54402 | Down | -0.2524670204 |
| GSE9593 | Up | 0.0114758326 |
| GSE43922 | Down | -0.0524657051 |
| GSE24585 | Up | 0.1768697531 |
| GSE37065 | Down | -0.2653197623 |
| GSE28863_A1 | Down | -0.0120470969 |
| GSE28863_A2 | Down | -0.7238913467 |
| GSE28863_A3 | Down | -0.9029299188 |
| GSE28863_A4 | Up | 0.1214197920 |
| GSE48662 | Down | -0.1625710016 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-877-5p | MIMAT0004949 | MIRT037303 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037487 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-425-5p | MIMAT0003393 | MIRT039345 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043170 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-148a-3p | MIMAT0000243 | MIRT048032 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT048927 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050860 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1260b | MIMAT0015041 | MIRT052685 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 23360310 | The peripheral heterochromatic compartment (PHC) becomes less prominent, and centromere structure becomes notably enlarged |
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