HCSGD entry for PGF

1. General information

Official gene symbolPGF
Entrez ID5228
Gene full nameplacental growth factor
Other gene symbolsD12S1900 PGFL PLGF PlGF-2 SHGC-10760
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001658Branching involved in ureteric bud morphogenesisIEAbiological_process
GO:0001666Response to hypoxiaIEAbiological_process
GO:0001938Positive regulation of endothelial cell proliferationIEAbiological_process
GO:0002040Sprouting angiogenesisIEAbiological_process
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0007165Signal transductionTASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0007565Female pregnancyIEAbiological_process
GO:0008083Growth factor activityIEA IMPmolecular_function
GO:0008201Heparin bindingIEAmolecular_function
GO:0008284Positive regulation of cell proliferationIMPbiological_process
GO:0016020MembraneIEAcellular_component
GO:0030154Cell differentiationIEAbiological_process
GO:0031100Organ regenerationIEAbiological_process
GO:0032870Cellular response to hormone stimulusIEAbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0045766Positive regulation of angiogenesisIEAbiological_process
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0048010Vascular endothelial growth factor receptor signaling pathwayTASbiological_process
GO:0051781Positive regulation of cell divisionIEAbiological_process
GO:0060688Regulation of morphogenesis of a branching structureIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.08769006120.29945881240.62179151401.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0762137194
GSE13712_SHEARUp0.8065481052
GSE13712_STATICUp0.0165900164
GSE19018Up0.0737763335
GSE19899_A1Down-0.0350279052
GSE19899_A2Up0.1677783036
PubMed_21979375_A1Down-0.4037136342
PubMed_21979375_A2Up0.2339262955
GSE35957Down-1.1780271974
GSE36640Up0.0641122068
GSE54402Up0.0874217170
GSE9593Down-1.0107204549
GSE43922Up0.1568988265
GSE24585Up0.4058513578
GSE37065Down-0.1148136848
GSE28863_A1Up0.4727813472
GSE28863_A2Down-0.1821300047
GSE28863_A3Up0.3377660775
GSE28863_A4Up0.0052904602
GSE48662Up0.9708969593

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

AfliberceptDB08885 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.