HCSGD entry for PGC

1. General information

Official gene symbolPGC
Entrez ID5225
Gene full nameprogastricsin (pepsinogen C)
Other gene symbolsPEPC PGII
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004190Aspartic-type endopeptidase activityIEAmolecular_function
GO:0005615Extracellular spaceTAScellular_component
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0007586DigestionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.58261642410.89213186050.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0944400600
GSE13712_SHEARDown-0.0083772503
GSE13712_STATICDown-0.0434914094
GSE19018Up0.0856004067
GSE19899_A1Up0.1242412559
GSE19899_A2Up0.1740286416
PubMed_21979375_A1Down-0.0455260433
PubMed_21979375_A2Down-0.0669980014
GSE35957Up0.2740792083
GSE36640Up0.1254454127
GSE54402Up0.0017077773
GSE9593Up0.0487976907
GSE43922Up0.1227085742
GSE24585Down-0.0901386271
GSE37065Down-0.0164563042
GSE28863_A1Up0.0285470144
GSE28863_A2Up0.0614894518
GSE28863_A3Up0.1083715295
GSE28863_A4Up0.0374913668
GSE48662Up0.0516155709

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.