HCSGD entry for ATP8B1

1. General information

Official gene symbolATP8B1
Entrez ID5205
Gene full nameATPase, aminophospholipid transporter, class I, type 8B, member 1
Other gene symbolsATPIC BRIC FIC1 ICP1 PFIC PFIC1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000287Magnesium ion bindingIEAmolecular_function
GO:0004012Phospholipid-translocating ATPase activityIEA TASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneNAScellular_component
GO:0006200ATP catabolic processRCA TASbiological_process
GO:0008206Bile acid metabolic processIEAbiological_process
GO:0015721Bile acid and bile salt transportNASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016324Apical plasma membraneIDAcellular_component
GO:0016887ATPase activityRCAmolecular_function
GO:0019829Cation-transporting ATPase activityIEAmolecular_function
GO:0031526Brush border membraneIEAcellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0045332Phospholipid translocationNASbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIMPbiological_process
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.66555948860.00042220280.99999024730.0382505155

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.4477930760
GSE13712_SHEARUp0.1061012028
GSE13712_STATICDown-0.1975998555
GSE19018Down-0.0663298136
GSE19899_A1Down-2.5194131794
GSE19899_A2Down-0.7439405871
PubMed_21979375_A1Down-3.5826995893
PubMed_21979375_A2Down-1.4737184355
GSE35957Up0.9390960785
GSE36640Down-0.5211474690
GSE54402Down-1.9224807515
GSE9593Up0.2194036991
GSE43922Down-1.6716171390
GSE24585Down-0.8641306257
GSE37065Down-0.6179857020
GSE28863_A1Down-0.0642907463
GSE28863_A2Up1.2651493031
GSE28863_A3Down-0.4139762005
GSE28863_A4Up0.3116988465
GSE48662Down-0.6145770081

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.