HCSGD entry for PFDN2
1. General information
| Official gene symbol | PFDN2 |
|---|---|
| Entrez ID | 5202 |
| Gene full name | prefoldin subunit 2 |
| Other gene symbols | PFD2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0006457 | Protein folding | NAS TAS | biological_process |
| GO:0016272 | Prefoldin complex | NAS | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0051082 | Unfolded protein binding | NAS | molecular_function |
| GO:0051084 | 'de novo' posttranslational protein folding | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0183520003 | 0.3684309943 | 0.3317603022 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.7550587345 |
| GSE13712_SHEAR | Up | 0.1212651259 |
| GSE13712_STATIC | Up | 0.1640677586 |
| GSE19018 | Down | -0.2340251118 |
| GSE19899_A1 | Up | 1.6155037895 |
| GSE19899_A2 | Up | 0.8003718149 |
| PubMed_21979375_A1 | Up | 1.3844335760 |
| PubMed_21979375_A2 | Up | 0.6274314049 |
| GSE35957 | Down | -0.2517295492 |
| GSE36640 | Down | -0.3124041321 |
| GSE54402 | Up | 1.2038472734 |
| GSE9593 | Down | -0.2364465820 |
| GSE43922 | Up | 0.4807291596 |
| GSE24585 | Down | -0.3563328425 |
| GSE37065 | Down | -0.0255792974 |
| GSE28863_A1 | Down | -0.6295890492 |
| GSE28863_A2 | Down | -0.0983460015 |
| GSE28863_A3 | Down | -0.0210409160 |
| GSE28863_A4 | Down | -0.0677481411 |
| GSE48662 | Down | -0.2900002267 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016457 | Proteomics | Functional MTI (Weak) | 21512034 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038880 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039815 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-210-3p | MIMAT0000267 | MIRT047002 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049268 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
