HCSGD entry for PEX14
1. General information
| Official gene symbol | PEX14 |
|---|---|
| Entrez ID | 5195 |
| Gene full name | peroxisomal biogenesis factor 14 |
| Other gene symbols | NAPP2 PBD13A Pex14p dJ734G22.2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003714 | Transcription corepressor activity | IDA | molecular_function |
| GO:0005102 | Receptor binding | IPI | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IDA | cellular_component |
| GO:0005634 | Nucleus | NAS | cellular_component |
| GO:0005777 | Peroxisome | IDA | cellular_component |
| GO:0005778 | Peroxisomal membrane | IDA IEA ISS | cellular_component |
| GO:0006461 | Protein complex assembly | IDA | biological_process |
| GO:0007031 | Peroxisome organization | IGI ISS | biological_process |
| GO:0008017 | Microtubule binding | IDA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA ISS | cellular_component |
| GO:0016558 | Protein import into peroxisome matrix | IMP | biological_process |
| GO:0016560 | Protein import into peroxisome matrix, docking | IEA | biological_process |
| GO:0016561 | Protein import into peroxisome matrix, translocation | IDA | biological_process |
| GO:0032091 | Negative regulation of protein binding | IDA | biological_process |
| GO:0034453 | Microtubule anchoring | IDA | biological_process |
| GO:0036250 | Peroxisome transport along microtubule | IDA | biological_process |
| GO:0043234 | Protein complex | IDA IEA ISS | cellular_component |
| GO:0043433 | Negative regulation of sequence-specific DNA binding transcription factor activity | IDA | biological_process |
| GO:0044721 | Protein import into peroxisome matrix, substrate release | IDA | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0047485 | Protein N-terminus binding | IPI | molecular_function |
| GO:0048487 | Beta-tubulin binding | IPI | molecular_function |
| GO:0051260 | Protein homooligomerization | IDA | biological_process |
| GO:1901094 | Negative regulation of protein homotetramerization | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0718559591 | 0.9814434824 | 0.5715393848 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0942090489 |
| GSE13712_SHEAR | Up | 0.0956147698 |
| GSE13712_STATIC | Up | 0.2299402441 |
| GSE19018 | Up | 0.0560322477 |
| GSE19899_A1 | Up | 0.0810845607 |
| GSE19899_A2 | Up | 0.6101139348 |
| PubMed_21979375_A1 | Up | 1.2737063384 |
| PubMed_21979375_A2 | Up | 1.1179590458 |
| GSE35957 | Up | 0.0260341891 |
| GSE36640 | Up | 0.0051035317 |
| GSE54402 | Up | 0.0139082473 |
| GSE9593 | Up | 0.0270201870 |
| GSE43922 | Up | 0.0457681147 |
| GSE24585 | Up | 0.1245303353 |
| GSE37065 | Up | 0.0395243655 |
| GSE28863_A1 | Down | -0.0223046408 |
| GSE28863_A2 | Up | 0.3074374249 |
| GSE28863_A3 | Up | 0.1219183221 |
| GSE28863_A4 | Down | -0.0371842392 |
| GSE48662 | Up | 0.3183995643 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT031741 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040066 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052548 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
