HCSGD entry for SIX4
1. General information
| Official gene symbol | SIX4 |
|---|---|
| Entrez ID | 51804 |
| Gene full name | SIX homeobox 4 |
| Other gene symbols | AREC3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0007519 | Skeletal muscle tissue development | IEA | biological_process |
| GO:0008582 | Regulation of synaptic growth at neuromuscular junction | IEA | biological_process |
| GO:0009653 | Anatomical structure morphogenesis | TAS | biological_process |
| GO:0032880 | Regulation of protein localization | IEA | biological_process |
| GO:0042472 | Inner ear morphogenesis | IEA | biological_process |
| GO:0043524 | Negative regulation of neuron apoptotic process | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0048538 | Thymus development | IEA | biological_process |
| GO:0048699 | Generation of neurons | IEA | biological_process |
| GO:0048701 | Embryonic cranial skeleton morphogenesis | IEA | biological_process |
| GO:0051451 | Myoblast migration | IEA | biological_process |
| GO:0072075 | Metanephric mesenchyme development | IEA | biological_process |
| GO:0072095 | Regulation of branch elongation involved in ureteric bud branching | IEA | biological_process |
| GO:0072107 | Positive regulation of ureteric bud formation | IEA | biological_process |
| GO:0090190 | Positive regulation of branching involved in ureteric bud morphogenesis | IEA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9655012765 | 0.0290322746 | 0.9999902473 | 0.3229748521 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1883086338 |
| GSE13712_SHEAR | Down | -0.2570029928 |
| GSE13712_STATIC | Down | -0.3271868151 |
| GSE19018 | Up | 0.2160474838 |
| GSE19899_A1 | Down | -0.2039551266 |
| GSE19899_A2 | Down | -0.7785227335 |
| PubMed_21979375_A1 | Down | -0.9090525615 |
| PubMed_21979375_A2 | Down | -0.5180639740 |
| GSE35957 | Down | -0.1442200931 |
| GSE36640 | Down | -0.7701066796 |
| GSE54402 | Down | -0.6951249589 |
| GSE9593 | Down | -0.2042104110 |
| GSE43922 | Down | -0.2196388754 |
| GSE24585 | Up | 0.0139520253 |
| GSE37065 | Up | 0.0050786906 |
| GSE28863_A1 | Down | -0.0922069338 |
| GSE28863_A2 | Down | -0.1417234913 |
| GSE28863_A3 | Down | -0.1228957100 |
| GSE28863_A4 | Up | 0.1299884872 |
| GSE48662 | Up | 0.1997363902 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020134 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022314 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024411 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026229 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026229 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031112 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-320a | MIMAT0000510 | MIRT044638 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
