HCSGD entry for PENK
1. General information
| Official gene symbol | PENK |
|---|---|
| Entrez ID | 5179 |
| Gene full name | proenkephalin |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001515 | Opioid peptide activity | IEA | molecular_function |
| GO:0001662 | Behavioral fear response | IEA | biological_process |
| GO:0001964 | Startle response | IEA | biological_process |
| GO:0002118 | Aggressive behavior | IEA | biological_process |
| GO:0005184 | Neuropeptide hormone activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | IEA TAS | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007218 | Neuropeptide signaling pathway | IEA | biological_process |
| GO:0007626 | Locomotory behavior | IEA | biological_process |
| GO:0019233 | Sensory perception of pain | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4330078227 | 0.0928068994 | 0.9999902473 | 0.5800820988 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2989284264 |
| GSE13712_SHEAR | Down | -0.1173867771 |
| GSE13712_STATIC | Down | -0.1634091191 |
| GSE19018 | Up | 0.2019164698 |
| GSE19899_A1 | Down | -0.0746196489 |
| GSE19899_A2 | Down | -1.1939996670 |
| PubMed_21979375_A1 | Down | -0.0395786524 |
| PubMed_21979375_A2 | Down | -0.8990411648 |
| GSE35957 | Down | -0.0834623839 |
| GSE36640 | Down | -0.1569377671 |
| GSE54402 | Down | -0.7794039457 |
| GSE9593 | Down | -0.5166017503 |
| GSE43922 | Up | 0.0376390774 |
| GSE24585 | Down | -0.1611272913 |
| GSE37065 | Up | 0.5070348054 |
| GSE28863_A1 | Down | -0.0555785350 |
| GSE28863_A2 | Up | 0.1262044535 |
| GSE28863_A3 | Up | 0.5269709596 |
| GSE28863_A4 | Up | 0.0545634516 |
| GSE48662 | Up | 0.2828741601 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
