HCSGD entry for ARID4B
1. General information
| Official gene symbol | ARID4B |
|---|---|
| Entrez ID | 51742 |
| Gene full name | AT rich interactive domain 4B (RBP1-like) |
| Other gene symbols | BCAA BRCAA1 RBBP1L1 RBP1L1 SAP180 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006349 | Regulation of gene expression by genetic imprinting | IEA | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0034773 | Histone H4-K20 trimethylation | IEA | biological_process |
| GO:0036124 | Histone H3-K9 trimethylation | IEA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2730003191 | 0.7048304396 | 0.9702070937 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0368836581 |
| GSE13712_SHEAR | Up | 0.0069871032 |
| GSE13712_STATIC | Down | -0.0160425989 |
| GSE19018 | Up | 0.0548682924 |
| GSE19899_A1 | Up | 0.0791762860 |
| GSE19899_A2 | Down | -0.2128785474 |
| PubMed_21979375_A1 | Down | -0.1125418330 |
| PubMed_21979375_A2 | Down | -0.0194441266 |
| GSE35957 | Up | 0.1314323203 |
| GSE36640 | Up | 0.1374998667 |
| GSE54402 | Up | 0.0670745233 |
| GSE9593 | Down | -0.0070408510 |
| GSE43922 | Up | 0.0219006427 |
| GSE24585 | Up | 0.4867369087 |
| GSE37065 | Up | 0.2152233035 |
| GSE28863_A1 | Up | 0.7231657232 |
| GSE28863_A2 | Up | 0.6319486184 |
| GSE28863_A3 | Down | -0.4415909270 |
| GSE28863_A4 | Down | -0.2066628067 |
| GSE48662 | Down | -0.2583996204 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-106a-5p | MIMAT0000103 | MIRT004028 | Luciferase reporter assay//Western blot;Other | Functional MTI | 17575136 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT004065 | Luciferase reporter assay | Non-Functional MTI | 17575136 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT004065 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-20b-5p | MIMAT0001413 | MIRT004072 | Luciferase reporter assay//Western blot;Other | Functional MTI | 17575136 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT004089 | Luciferase reporter assay | Non-Functional MTI | 17575136 |
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020213 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028050 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-17-3p | MIMAT0000071 | MIRT050768 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 24223226 | However, it is not clear how BCAA supplementation prevents the incidence of liver cancer in patients with cirrhosis |
| 18193082 | Both RBP1 and the highly related protein BCAA play a role in the induction of growth arrest and cellular senescence via mechanisms involving transcriptional repression |
Entries Per Page
Displaying Page of
