HCSGD entry for WBP11


1. General information

Official gene symbolWBP11
Entrez ID51729
Gene full nameWW domain binding protein 11
Other gene symbolsNPWBP SIPP1 WBP-11
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003697Single-stranded DNA bindingTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusTAScellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0006364RRNA processingIEAbiological_process
GO:0006396RNA processingIEAbiological_process
GO:0006397MRNA processingIEAbiological_process
GO:0008380RNA splicingIEAbiological_process
GO:0008599Protein phosphatase type 1 regulator activityIEAmolecular_function
GO:0016607Nuclear speckIEAcellular_component
GO:0050699WW domain bindingIPImolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.74652423920.42662040580.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0138859151
GSE13712_SHEARDown-0.1526512382
GSE13712_STATICDown-0.1794127917
GSE19018Down-0.0057928226
GSE19899_A1Down-0.0523532243
GSE19899_A2Down-0.0809428688
PubMed_21979375_A1Up0.2638906500
PubMed_21979375_A2Up0.3543993135
GSE35957Down-0.0296872336
GSE36640Down-0.5669580504
GSE54402Up0.0328854819
GSE9593Up0.0194959015
GSE43922Down-0.0413214408
GSE24585Up0.1076875920
GSE37065Up0.1177507342
GSE28863_A1Up0.2671851213
GSE28863_A2Up0.0384988446
GSE28863_A3Up0.0752809794
GSE28863_A4Down-0.1413454752
GSE48662Down-0.3181570014

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-34a-5pMIMAT0000255MIRT025244ProteomicsFunctional MTI (Weak)21566225
hsa-miR-98-5pMIMAT0000096MIRT027410MicroarrayFunctional MTI (Weak)19088304
hsa-miR-16-5pMIMAT0000069MIRT031437ProteomicsFunctional MTI (Weak)18668040
hsa-miR-877-5pMIMAT0004949MIRT037321CLASHFunctional MTI (Weak)23622248
hsa-let-7c-5pMIMAT0000064MIRT051869CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT052331CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.