HCSGD entry for UIMC1


1. General information

Official gene symbolUIMC1
Entrez ID51720
Gene full nameubiquitin interaction motif containing 1
Other gene symbolsRAP80 X2HRIP110
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0006302Double-strand break repairIMPbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0010212Response to ionizing radiationIMPbiological_process
GO:0031572G2 DNA damage checkpointIMPbiological_process
GO:0042393Histone bindingIDAmolecular_function
GO:0045739Positive regulation of DNA repairIMPbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
GO:0046965Retinoid X receptor bindingIEAmolecular_function
GO:0070530K63-linked polyubiquitin bindingIDAmolecular_function
GO:0070531BRCA1-A complexIDAcellular_component
GO:0070537Histone H2A K63-linked deubiquitinationIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.90716809390.10247842410.99999024730.6135883985

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2555589879
GSE13712_SHEARDown-0.0920811472
GSE13712_STATICDown-0.2426548768
GSE19018Down-0.0092601346
GSE19899_A1Down-0.0316985225
GSE19899_A2Down-0.0648206190
PubMed_21979375_A1Down-0.1986139221
PubMed_21979375_A2Up0.4053535695
GSE35957Down-0.6826838801
GSE36640Down-0.3391421830
GSE54402Up0.1368707887
GSE9593Down-0.3570102378
GSE43922Up0.1056799543
GSE24585Down-0.0367414745
GSE37065Down-0.1812063131
GSE28863_A1Down-0.0699258536
GSE28863_A2Down-0.1886801834
GSE28863_A3Down-0.4169254241
GSE28863_A4Down-0.1504776352
GSE48662Down-0.2933057948

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.