HCSGD entry for TMEM66
1. General information
| Official gene symbol | TMEM66 |
|---|---|
| Entrez ID | 51669 |
| Gene full name | transmembrane protein 66 |
| Other gene symbols | FOAP-7 SARAF XTP3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0015279 | Store-operated calcium channel activity | IDA | molecular_function |
| GO:0030176 | Integral component of endoplasmic reticulum membrane | IDA | cellular_component |
| GO:0034220 | Ion transmembrane transport | IDA | biological_process |
| GO:0055085 | Transmembrane transport | IDA | biological_process |
| GO:0070588 | Calcium ion transmembrane transport | IDA | biological_process |
| GO:2001256 | Regulation of store-operated calcium entry | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0128311272 | 0.9784891911 | 0.2830914501 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5299640089 |
| GSE13712_SHEAR | Down | -0.0967585480 |
| GSE13712_STATIC | Down | -0.1187284595 |
| GSE19018 | Up | 0.5306804071 |
| GSE19899_A1 | Up | 0.3427180500 |
| GSE19899_A2 | Up | 0.5423869389 |
| PubMed_21979375_A1 | Up | 0.0139058568 |
| PubMed_21979375_A2 | Up | 0.2022577792 |
| GSE35957 | Up | 0.2628694958 |
| GSE36640 | Up | 1.4495868887 |
| GSE54402 | Up | 0.0010626551 |
| GSE9593 | Up | 0.3583916744 |
| GSE43922 | Up | 0.3429870775 |
| GSE24585 | Up | 0.1506270125 |
| GSE37065 | Up | 0.2272579955 |
| GSE28863_A1 | Up | 0.1433283873 |
| GSE28863_A2 | Up | 0.3762614689 |
| GSE28863_A3 | Down | -0.4077768080 |
| GSE28863_A4 | Down | -0.0186637379 |
| GSE48662 | Up | 0.1943291202 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024777 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026643 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040141 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-148b-3p | MIMAT0000759 | MIRT043595 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049713 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050562 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
