HCSGD entry for FAM96B
1. General information
| Official gene symbol | FAM96B |
|---|---|
| Entrez ID | 51647 |
| Gene full name | family with sequence similarity 96, member B |
| Other gene symbols | MIP18 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005819 | Spindle | IDA | cellular_component |
| GO:0007059 | Chromosome segregation | IMP | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0071817 | MMXD complex | IDA | cellular_component |
| GO:0097361 | CIA complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1709578208 | 0.4635096843 | 0.8133994038 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4660368236 |
| GSE13712_SHEAR | Down | -0.2688496442 |
| GSE13712_STATIC | Down | -0.0647934342 |
| GSE19018 | Down | -0.2804483680 |
| GSE19899_A1 | Up | 0.3467261643 |
| GSE19899_A2 | Up | 0.1287482181 |
| PubMed_21979375_A1 | Up | 1.7582259005 |
| PubMed_21979375_A2 | Down | -0.0123302042 |
| GSE35957 | Down | -0.6161020130 |
| GSE36640 | Up | 0.0367073144 |
| GSE54402 | Up | 0.7325972530 |
| GSE9593 | Down | -0.1617444361 |
| GSE43922 | Up | 0.2163201241 |
| GSE24585 | Down | -0.1611245519 |
| GSE37065 | Down | -0.0613286564 |
| GSE28863_A1 | Down | -0.3406069004 |
| GSE28863_A2 | Down | -0.0370979523 |
| GSE28863_A3 | Down | -0.1340096107 |
| GSE28863_A4 | Up | 0.2534404156 |
| GSE48662 | Down | -0.0955959769 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT021001 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT032014 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 24041693 | Identification of FAM96B as a novel prelamin A binding partner |
| 24041693 | Here we carried out a yeast two-hybrid screen using a human skeletal muscle cDNA library to search for prelamin A binding partners, and identified FAM96B as a prelamin A binding partner |
| 24041693 | Furthermore, co-localization experiments by fluorescent confocal microscopy revealed that FAM96B colocalized with prelamin A in HEK-293 cells |
| 24041693 | Taken together, our data demonstrated the physical interaction between FAM96B and prelamin A, which may provide some clues to the mechanisms of prelamin A in premature aging |
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