HCSGD entry for MED15
1. General information
| Official gene symbol | MED15 |
|---|---|
| Entrez ID | 51586 |
| Gene full name | mediator complex subunit 15 |
| Other gene symbols | ARC105 CAG7A CTG7A PCQAP TIG-1 TIG1 TNRC7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001104 | RNA polymerase II transcription cofactor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016592 | Mediator complex | IEA | cellular_component |
| GO:0019827 | Stem cell maintenance | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0709048364 | 0.9010182174 | 0.5682966504 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1177100031 |
| GSE13712_SHEAR | Up | 0.1123477037 |
| GSE13712_STATIC | Up | 0.1477964727 |
| GSE19018 | Up | 0.2412071103 |
| GSE19899_A1 | Down | -0.2196413301 |
| GSE19899_A2 | Up | 0.3818462648 |
| PubMed_21979375_A1 | Up | 1.1467769517 |
| PubMed_21979375_A2 | Up | 0.9700285298 |
| GSE35957 | Down | -0.0815035193 |
| GSE36640 | Up | 0.0710012744 |
| GSE54402 | Up | 0.3518124498 |
| GSE9593 | Up | 0.0726134244 |
| GSE43922 | Down | -0.0268687818 |
| GSE24585 | Up | 0.2172653642 |
| GSE37065 | Down | -0.0896466124 |
| GSE28863_A1 | Up | 0.1267013206 |
| GSE28863_A2 | Up | 0.2721944807 |
| GSE28863_A3 | Up | 0.2012869410 |
| GSE28863_A4 | Down | -0.0179043294 |
| GSE48662 | Up | 0.1188585775 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-744-5p | MIMAT0004945 | MIRT037735 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042132 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042961 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045202 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT047371 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
