HCSGD entry for PCF11
1. General information
| Official gene symbol | PCF11 |
|---|---|
| Entrez ID | 51585 |
| Gene full name | PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae) |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000398 | MRNA splicing, via spliceosome | TAS | biological_process |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005849 | MRNA cleavage factor complex | NAS | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006369 | Termination of RNA polymerase II transcription | TAS | biological_process |
| GO:0006379 | MRNA cleavage | NAS | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0031124 | MRNA 3'-end processing | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6601751567 | 0.0582775312 | 0.9999902473 | 0.4540013909 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1374582075 |
| GSE13712_SHEAR | Down | -0.2480103477 |
| GSE13712_STATIC | Down | -0.2707867486 |
| GSE19018 | Down | -1.1718591365 |
| GSE19899_A1 | Down | -0.2869395647 |
| GSE19899_A2 | Down | -0.3712494689 |
| PubMed_21979375_A1 | Down | -0.2207155689 |
| PubMed_21979375_A2 | Down | -0.4328853126 |
| GSE35957 | Down | -0.2574726404 |
| GSE36640 | Down | -0.3766866368 |
| GSE54402 | Down | -0.2123706928 |
| GSE9593 | Down | -0.1918584648 |
| GSE43922 | Up | 0.0977454020 |
| GSE24585 | Down | -0.0510571858 |
| GSE37065 | Up | 0.1213302197 |
| GSE28863_A1 | Up | 0.7428167255 |
| GSE28863_A2 | Up | 0.7105498596 |
| GSE28863_A3 | Down | -0.0738238496 |
| GSE28863_A4 | Up | 0.2131170564 |
| GSE48662 | Up | 0.1205360368 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-15a-5p | MIMAT0000068 | MIRT051315 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051836 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
