HCSGD entry for PDGFRL
1. General information
| Official gene symbol | PDGFRL |
|---|---|
| Entrez ID | 5157 |
| Gene full name | platelet-derived growth factor receptor-like |
| Other gene symbols | PDGRL PRLTS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004992 | Platelet activating factor receptor activity | TAS | molecular_function |
| GO:0005019 | Platelet-derived growth factor beta-receptor activity | TAS | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0006468 | Protein phosphorylation | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0016310 | Phosphorylation | TAS | biological_process |
| GO:0018108 | Peptidyl-tyrosine phosphorylation | TAS | biological_process |
| GO:0035791 | Platelet-derived growth factor receptor-beta signaling pathway | TAS | biological_process |
| GO:0036120 | Cellular response to platelet-derived growth factor stimulus | TAS | biological_process |
| GO:0048008 | Platelet-derived growth factor receptor signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3218735648 | 0.0037411573 | 0.9999902473 | 0.1241752837 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6923625512 |
| GSE13712_SHEAR | Down | -1.8227065792 |
| GSE13712_STATIC | Down | -1.0068268229 |
| GSE19018 | Down | -0.0795197208 |
| GSE19899_A1 | Down | -0.6581277200 |
| GSE19899_A2 | Down | -0.9971661281 |
| PubMed_21979375_A1 | Down | -1.3917124768 |
| PubMed_21979375_A2 | Down | -1.3377810359 |
| GSE35957 | Down | -0.3732883069 |
| GSE36640 | Up | 0.0502393308 |
| GSE54402 | Down | -2.2484775965 |
| GSE9593 | Up | 0.1046693521 |
| GSE43922 | Down | -0.1689200948 |
| GSE24585 | Down | -0.2236947526 |
| GSE37065 | Up | 0.6421425252 |
| GSE28863_A1 | Up | 0.7863132444 |
| GSE28863_A2 | Up | 0.7057436896 |
| GSE28863_A3 | Up | 0.1355125323 |
| GSE28863_A4 | Up | 0.0518949669 |
| GSE48662 | Down | -0.4913521526 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029428 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050268 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
