HCSGD entry for PEX5L


1. General information

Official gene symbolPEX5L
Entrez ID51555
Gene full nameperoxisomal biogenesis factor 5-like
Other gene symbolsPEX5R PEX5RP PXR2 PXR2B TRIP8b
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000268Peroxisome targeting sequence bindingIDAmolecular_function
GO:0005052Peroxisome matrix targeting signal-1 bindingIBA IDAmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005778Peroxisomal membraneIBAcellular_component
GO:0005829CytosolIBA IDAcellular_component
GO:0016558Protein import into peroxisome matrixIBAbiological_process
GO:0016560Protein import into peroxisome matrix, dockingIBAbiological_process
GO:0030425DendriteIEAcellular_component
GO:0031267Small GTPase bindingIPImolecular_function
GO:0042391Regulation of membrane potentialIEAbiological_process
GO:0043235Receptor complexIDAcellular_component
GO:0043949Regulation of cAMP-mediated signalingISSbiological_process
GO:0045185Maintenance of protein locationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.56577642950.86941344170.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1020117380
GSE13712_SHEARUp0.0101426755
GSE13712_STATICDown-0.0985516949
GSE19018Up0.0441985380
GSE19899_A1Up0.0220078492
GSE19899_A2Down-0.1680132529
PubMed_21979375_A1Up0.1771986113
PubMed_21979375_A2Down-0.0831183676
GSE35957Up0.0384012028
GSE36640Down-0.0542852686
GSE54402Up0.0787879768
GSE9593Up0.0999380547
GSE43922Up0.0435599889
GSE24585Up0.1004122536
GSE37065Up0.3416663940
GSE28863_A1Up0.0917350180
GSE28863_A2Up0.0426598303
GSE28863_A3Up0.2405413158
GSE28863_A4Down-0.1107976389
GSE48662Up0.1017096382

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029375MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.