HCSGD entry for SCLY
1. General information
| Official gene symbol | SCLY |
|---|---|
| Entrez ID | 51540 |
| Gene full name | selenocysteine lyase |
| Other gene symbols | SCL hSCL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0006520 | Cellular amino acid metabolic process | TAS | biological_process |
| GO:0009000 | Selenocysteine lyase activity | IEA | molecular_function |
| GO:0016740 | Transferase activity | IEA | molecular_function |
| GO:0030170 | Pyridoxal phosphate binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6667906804 | 0.6444353482 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1304504594 |
| GSE13712_SHEAR | Up | 0.4244024853 |
| GSE13712_STATIC | Up | 0.3647465234 |
| GSE19018 | Down | -0.2544136984 |
| GSE19899_A1 | Down | -0.0582830362 |
| GSE19899_A2 | Up | 0.1697878060 |
| PubMed_21979375_A1 | Up | 0.5464805513 |
| PubMed_21979375_A2 | Up | 0.0565567166 |
| GSE35957 | Down | -0.0307213430 |
| GSE36640 | Down | -0.1067236700 |
| GSE54402 | Up | 0.1113182465 |
| GSE9593 | Down | -0.5371742170 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Down | -0.1373902571 |
| GSE28863_A2 | Up | 0.0206167376 |
| GSE28863_A3 | Down | -0.1066693212 |
| GSE28863_A4 | Down | -0.1363289013 |
| GSE48662 | Up | 0.0208354221 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT020017 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041424 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049587 | CLASH//qRT-PCR | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
