HCSGD entry for PDE9A
1. General information
| Official gene symbol | PDE9A |
|---|---|
| Entrez ID | 5152 |
| Gene full name | phosphodiesterase 9A |
| Other gene symbols | HSPDE9A2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004114 | 3',5'-cyclic-nucleotide phosphodiesterase activity | IEA TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005829 | Cytosol | IDA TAS | cellular_component |
| GO:0007165 | Signal transduction | IEA TAS | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0019934 | CGMP-mediated signaling | IEA | biological_process |
| GO:0032587 | Ruffle membrane | IEA | cellular_component |
| GO:0043204 | Perikaryon | IEA | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity | IEA | molecular_function |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6282489039 | 0.8338808062 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0296052415 |
| GSE13712_SHEAR | Down | -0.2594724757 |
| GSE13712_STATIC | Up | 0.0160574711 |
| GSE19018 | Up | 0.1525772629 |
| GSE19899_A1 | Down | -0.0253815065 |
| GSE19899_A2 | Up | 0.0967389167 |
| PubMed_21979375_A1 | Up | 0.1457314170 |
| PubMed_21979375_A2 | Up | 0.1592832837 |
| GSE35957 | Down | -0.1113347681 |
| GSE36640 | Up | 0.1576347049 |
| GSE54402 | Up | 0.0922185873 |
| GSE9593 | Up | 0.0873042591 |
| GSE43922 | Up | 0.0445930698 |
| GSE24585 | Down | -0.3772970464 |
| GSE37065 | Down | -0.1068619251 |
| GSE28863_A1 | Up | 0.0612475108 |
| GSE28863_A2 | Up | 0.0386406412 |
| GSE28863_A3 | Up | 0.2910027058 |
| GSE28863_A4 | Up | 0.0242266069 |
| GSE48662 | Up | 0.2024987006 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine | DB03597 | EXPT01826 |
| 3-isobutyl-1-methyl-7H-xanthine | DB07954 | - |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
