HCSGD entry for TRIAP1

1. General information

Official gene symbolTRIAP1
Entrez ID51499
Gene full nameTP53 regulated inhibitor of apoptosis 1
Other gene symbolsMDM35 P53CSV WF-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002039P53 bindingIPImolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005739MitochondrionIDAcellular_component
GO:0005758Mitochondrial intermembrane spaceIDAcellular_component
GO:0006810TransportIDAbiological_process
GO:0006869Lipid transportIDAbiological_process
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrestTASbiological_process
GO:0015914Phospholipid transportIDAbiological_process
GO:0030330DNA damage response, signal transduction by p53 class mediatorIDAbiological_process
GO:0034644Cellular response to UVIDAbiological_process
GO:0043066Negative regulation of apoptotic processIMPbiological_process
GO:0043154Negative regulation of cysteine-type endopeptidase activity involved in apoptotic processIMPbiological_process
GO:0043234Protein complexIDAcellular_component
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
GO:0090201Negative regulation of release of cytochrome c from mitochondriaIMPbiological_process
GO:0097035Regulation of membrane lipid distributionIMPbiological_process
GO:1902166Negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorIMPbiological_process
GO:1990050Phosphatidic acid transporter activityIDAmolecular_function
GO:2001140Positive regulation of phospholipid transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01944053800.85946612590.33931989391.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.9490207848
GSE13712_SHEARUp0.1407781450
GSE13712_STATICUp0.2431405109
GSE19018Up0.1868706540
GSE19899_A1Up0.9649882532
GSE19899_A2Up0.5119980030
PubMed_21979375_A1Up0.6531155585
PubMed_21979375_A2Up0.8801961516
GSE35957Down-0.2520850596
GSE36640Up0.1777203662
GSE54402Up0.1031329092
GSE9593Down-0.1832097948
GSE43922Up0.4640983267
GSE24585Up0.0037310361
GSE37065Up0.1804118984
GSE28863_A1Down-0.2803030219
GSE28863_A2Down-0.2727687506
GSE28863_A3Down-0.6270925357
GSE28863_A4Up0.1476867089
GSE48662Up0.1102304021

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.