HCSGD entry for SFMBT1


1. General information

Official gene symbolSFMBT1
Entrez ID51460
Gene full nameScm-like with four mbt domains 1
Other gene symbolsRU1 SFMBT
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003714Transcription corepressor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0007283SpermatogenesisIEAbiological_process
GO:0016568Chromatin modificationIEAbiological_process
GO:0030154Cell differentiationIEAbiological_process
GO:0042393Histone bindingIDAmolecular_function
GO:0045892Negative regulation of transcription, DNA-templatedIDA IMPbiological_process
GO:0048635Negative regulation of muscle organ developmentIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.27409217350.30414175370.97045737151.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0242396241
GSE13712_SHEARUp0.2479738911
GSE13712_STATICUp0.3523527828
GSE19018Down-0.1701637630
GSE19899_A1Up0.0813756772
GSE19899_A2Up0.0252508035
PubMed_21979375_A1Down-0.0723298192
PubMed_21979375_A2Down-0.2954457220
GSE35957Down-0.3489010566
GSE36640Down-1.2349118613
GSE54402Up0.0014988112
GSE9593Down-0.0272465614
GSE43922Down-0.2810433584
GSE24585Up0.2809082684
GSE37065Up0.2383521571
GSE28863_A1Up0.7185693707
GSE28863_A2Up0.7449625341
GSE28863_A3Down-0.4187263015
GSE28863_A4Down-0.0239698436
GSE48662Down-0.0323730851

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029891MicroarrayFunctional MTI (Weak)19088304
hsa-miR-26a-5pMIMAT0000082MIRT050135CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT052054CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.