HCSGD entry for REV1


1. General information

Official gene symbolREV1
Entrez ID51455
Gene full nameREV1, polymerase (DNA directed)
Other gene symbolsREV1L
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000287Magnesium ion bindingIEAmolecular_function
GO:0003684Damaged DNA bindingIEAmolecular_function
GO:0003887DNA-directed DNA polymerase activityIEA TASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0006260DNA replicationTASbiological_process
GO:0006261DNA-dependent DNA replicationTASbiological_process
GO:0006281DNA repairIEA TASbiological_process
GO:0009411Response to UVIDAbiological_process
GO:0017125Deoxycytidyl transferase activityIEAmolecular_function
GO:0042276Error-prone translesion synthesisTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.94700023560.13604266180.99999024730.7113188121

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0294140353
GSE13712_SHEARDown-0.2512991912
GSE13712_STATICDown-0.3002552494
GSE19018Down-0.0437155589
GSE19899_A1Up0.1310027062
GSE19899_A2Down-0.2080177766
PubMed_21979375_A1Down-0.0892940550
PubMed_21979375_A2Down-0.2454911319
GSE35957Up0.0211438897
GSE36640Up0.1056550680
GSE54402Up0.0211740637
GSE9593Down-0.0912465480
GSE43922Down-0.1522089354
GSE24585Up0.0037555130
GSE37065Up0.0392929807
GSE28863_A1Up0.1254075556
GSE28863_A2Up0.3089420644
GSE28863_A3Down-0.5439819023
GSE28863_A4Down-0.2660700079
GSE48662Down-0.4391055845

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-21-5pMIMAT0000076MIRT030984MicroarrayFunctional MTI (Weak)18591254
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.