HCSGD entry for PRRX2


1. General information

Official gene symbolPRRX2
Entrez ID51450
Gene full namepaired related homeobox 2
Other gene symbolsPMX2 PRX2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002053Positive regulation of mesenchymal cell proliferationIEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityNASmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006355Regulation of transcription, DNA-templatedNASbiological_process
GO:0030326Embryonic limb morphogenesisIEAbiological_process
GO:0042472Inner ear morphogenesisIEAbiological_process
GO:0042474Middle ear morphogenesisIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045880Positive regulation of smoothened signaling pathwayIEAbiological_process
GO:0048701Embryonic cranial skeleton morphogenesisIEAbiological_process
GO:0048844Artery morphogenesisIEAbiological_process
GO:0051216Cartilage developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99810414120.00075392270.99999024730.0516770833

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1901236882
GSE13712_SHEARDown-0.5592101768
GSE13712_STATICDown-0.7278167356
GSE19018Down-0.2115790542
GSE19899_A1Down-0.8598110732
GSE19899_A2Down-3.2463861807
PubMed_21979375_A1Down-1.0567527425
PubMed_21979375_A2Down-1.9442960497
GSE35957Down-1.2417652440
GSE36640Up0.0344920787
GSE54402Down-0.3499218607
GSE9593Down-1.4372753488
GSE43922Down-0.1573717844
GSE24585Up0.0105319917
GSE37065Down-0.2241537220
GSE28863_A1Down-0.2407571115
GSE28863_A2Down-0.8276885129
GSE28863_A3Up0.0961846777
GSE28863_A4Up0.0265187440
GSE48662Down-0.1570053453

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT023165MicroarrayFunctional MTI (Weak)18668037
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.