HCSGD entry for IP6K2
1. General information
| Official gene symbol | IP6K2 |
|---|---|
| Entrez ID | 51447 |
| Gene full name | inositol hexakisphosphate kinase 2 |
| Other gene symbols | IHPK2 PIUS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000832 | Inositol hexakisphosphate 5-kinase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006817 | Phosphate ion transport | IEA | biological_process |
| GO:0008440 | Inositol-1,4,5-trisphosphate 3-kinase activity | IEA | molecular_function |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0030308 | Negative regulation of cell growth | IMP | biological_process |
| GO:0043065 | Positive regulation of apoptotic process | IMP | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0043647 | Inositol phosphate metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045111 | Intermediate filament cytoskeleton | IDA | cellular_component |
| GO:0046854 | Phosphatidylinositol phosphorylation | IDA | biological_process |
| GO:0052723 | Inositol hexakisphosphate 1-kinase activity | IEA | molecular_function |
| GO:0052724 | Inositol hexakisphosphate 3-kinase activity | IEA | molecular_function |
| GO:0060337 | Type I interferon signaling pathway | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0495944797 | 0.8304062764 | 0.4884320614 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6272452448 |
| GSE13712_SHEAR | Up | 0.0819286732 |
| GSE13712_STATIC | Up | 0.3882275812 |
| GSE19018 | Down | -0.1095515310 |
| GSE19899_A1 | Up | 0.2176740493 |
| GSE19899_A2 | Up | 0.4967761257 |
| PubMed_21979375_A1 | Down | -0.5514447892 |
| PubMed_21979375_A2 | Up | 0.1348603211 |
| GSE35957 | Down | -0.3691687296 |
| GSE36640 | Up | 0.7316688315 |
| GSE54402 | Up | 0.4088351377 |
| GSE9593 | Down | -0.3376145278 |
| GSE43922 | Up | 0.3908474016 |
| GSE24585 | Up | 0.5457341611 |
| GSE37065 | Up | 0.2519189883 |
| GSE28863_A1 | Down | -0.0218098965 |
| GSE28863_A2 | Up | 0.0567630694 |
| GSE28863_A3 | Down | -0.2210238491 |
| GSE28863_A4 | Down | -0.1498636916 |
| GSE48662 | Down | -0.1012986625 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT003850 | Microarray//Microarray;Other | Functional MTI (Weak) | 15685193 |
| hsa-miR-1 | MIMAT0000416 | MIRT003850 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027801 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-125a-3p | MIMAT0004602 | MIRT038635 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040826 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | NA | hsa-miR-1 | 15685193 |
Entries Per Page
Displaying Page of
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
