HCSGD entry for ANAPC7
1. General information
| Official gene symbol | ANAPC7 |
|---|---|
| Entrez ID | 51434 |
| Gene full name | anaphase promoting complex subunit 7 |
| Other gene symbols | APC7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005680 | Anaphase-promoting complex | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0007094 | Mitotic spindle assembly checkpoint | TAS | biological_process |
| GO:0019903 | Protein phosphatase binding | IPI | molecular_function |
| GO:0031145 | Anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | TAS | biological_process |
| GO:0051436 | Negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | TAS | biological_process |
| GO:0051437 | Positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | TAS | biological_process |
| GO:0051439 | Regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | TAS | biological_process |
| GO:0070979 | Protein K11-linked ubiquitination | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7301271342 | 0.3921466016 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2328109618 |
| GSE13712_SHEAR | Up | 0.1641223543 |
| GSE13712_STATIC | Up | 0.1322556965 |
| GSE19018 | Down | -0.6613818272 |
| GSE19899_A1 | Down | -0.1039717908 |
| GSE19899_A2 | Up | 0.2569220677 |
| PubMed_21979375_A1 | Down | -0.8505314440 |
| PubMed_21979375_A2 | Up | 0.2206202354 |
| GSE35957 | Down | -0.2275365442 |
| GSE36640 | Up | 0.1760578575 |
| GSE54402 | Down | -0.0932432398 |
| GSE9593 | Down | -0.0293810361 |
| GSE43922 | Down | -0.0495468811 |
| GSE24585 | Down | -0.1002431256 |
| GSE37065 | Down | -0.0580952386 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.1103605484 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022598 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038814 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-766-3p | MIMAT0003888 | MIRT039011 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041625 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044330 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
