HCSGD entry for PPME1
1. General information
| Official gene symbol | PPME1 |
|---|---|
| Entrez ID | 51400 |
| Gene full name | protein phosphatase methylesterase 1 |
| Other gene symbols | PME-1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004864 | Protein phosphatase inhibitor activity | TAS | molecular_function |
| GO:0006482 | Protein demethylation | IDA IEA | biological_process |
| GO:0008601 | Protein phosphatase type 2A regulator activity | TAS | molecular_function |
| GO:0019903 | Protein phosphatase binding | IDA | molecular_function |
| GO:0043086 | Negative regulation of catalytic activity | TAS | biological_process |
| GO:0050790 | Regulation of catalytic activity | TAS | biological_process |
| GO:0051721 | Protein phosphatase 2A binding | IDA | molecular_function |
| GO:0051722 | Protein C-terminal methylesterase activity | IDA | molecular_function |
| GO:0052689 | Carboxylic ester hydrolase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1963142586 | 0.3202337107 | 0.8576747552 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.6059742875 |
| GSE13712_SHEAR | Down | -0.1861832746 |
| GSE13712_STATIC | Up | 0.0094338857 |
| GSE19018 | Up | 0.6038573858 |
| GSE19899_A1 | Down | -0.0901860557 |
| GSE19899_A2 | Up | 0.2650219824 |
| PubMed_21979375_A1 | Up | 0.8139443595 |
| PubMed_21979375_A2 | Up | 0.7975623331 |
| GSE35957 | Down | -0.5206800136 |
| GSE36640 | Up | 0.0753518067 |
| GSE54402 | Up | 0.1919935813 |
| GSE9593 | Up | 0.1219609015 |
| GSE43922 | Up | 0.2144699303 |
| GSE24585 | Up | 0.1633540266 |
| GSE37065 | Up | 0.1675119284 |
| GSE28863_A1 | Down | -0.0138293417 |
| GSE28863_A2 | Down | -0.3454704212 |
| GSE28863_A3 | Down | -0.4793487918 |
| GSE28863_A4 | Down | -0.0419796076 |
| GSE48662 | Up | 0.1342249628 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
