HCSGD entry for UCHL5

1. General information

Official gene symbolUCHL5
Entrez ID51377
Gene full nameubiquitin carboxyl-terminal hydrolase L5
Other gene symbolsCGI-70 INO80R UCH-L5 UCH37
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000502Proteasome complexIEAcellular_component
GO:0004221Ubiquitin thiolesterase activityIEAmolecular_function
GO:0004843Ubiquitin-specific protease activityIDAmolecular_function
GO:0004866Endopeptidase inhibitor activityIMPmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolIDAcellular_component
GO:0006281DNA repairIEAbiological_process
GO:0006310DNA recombinationIEAbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0006511Ubiquitin-dependent protein catabolic processIEAbiological_process
GO:0007179Transforming growth factor beta receptor signaling pathwayTASbiological_process
GO:0008242Omega peptidase activityIEAmolecular_function
GO:0010466Negative regulation of peptidase activityIMPbiological_process
GO:0010951Negative regulation of endopeptidase activityIMPbiological_process
GO:0016579Protein deubiquitinationIDAbiological_process
GO:0021670Lateral ventricle developmentIEAbiological_process
GO:0030512Negative regulation of transforming growth factor beta receptor signaling pathwayTASbiological_process
GO:0030901Midbrain developmentIEAbiological_process
GO:0031011Ino80 complexIDAcellular_component
GO:0043086Negative regulation of catalytic activityIMPbiological_process
GO:0048853Forebrain morphogenesisIEAbiological_process
GO:0050790Regulation of catalytic activityIMPbiological_process
GO:0052547Regulation of peptidase activityIMPbiological_process
GO:0052548Regulation of endopeptidase activityIMPbiological_process
GO:0061136Regulation of proteasomal protein catabolic processIMPbiological_process
GO:0070628Proteasome bindingIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.93866690480.10739104520.99999024730.6269864271

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1447760015
GSE13712_SHEARUp0.1806107934
GSE13712_STATICUp0.1311401944
GSE19018Down-0.0798229618
GSE19899_A1Up0.2182178100
GSE19899_A2Down-0.3407867314
PubMed_21979375_A1Up0.2513924700
PubMed_21979375_A2Down-0.6329353466
GSE35957Down-0.2492612406
GSE36640Down-0.9254971308
GSE54402Up0.0412048257
GSE9593Down-0.3500210660
GSE43922Up0.0500169514
GSE24585Down-0.0547745367
GSE37065Down-0.1732708137
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.5121418225

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.