HCSGD entry for HOOK1
1. General information
| Official gene symbol | HOOK1 |
|---|---|
| Entrez ID | 51361 |
| Gene full name | hook homolog 1 (Drosophila) |
| Other gene symbols | HK1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0007032 | Endosome organization | IMP | biological_process |
| GO:0007040 | Lysosome organization | IMP | biological_process |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0007286 | Spermatid development | IEA | biological_process |
| GO:0008333 | Endosome to lysosome transport | IMP | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0030897 | HOPS complex | IDA | cellular_component |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0045022 | Early endosome to late endosome transport | IMP | biological_process |
| GO:0070695 | FHF complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6337686676 | 0.9172120854 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0291419105 |
| GSE13712_SHEAR | Up | 0.0775655094 |
| GSE13712_STATIC | Up | 0.0095784627 |
| GSE19018 | Up | 0.0334787907 |
| GSE19899_A1 | Up | 0.2265330551 |
| GSE19899_A2 | Up | 0.0724230756 |
| PubMed_21979375_A1 | Up | 0.0513944183 |
| PubMed_21979375_A2 | Up | 0.0091167242 |
| GSE35957 | Up | 0.0168289408 |
| GSE36640 | Up | 0.0385919105 |
| GSE54402 | Up | 0.0340927728 |
| GSE9593 | Up | 0.1767268532 |
| GSE43922 | Up | 0.0211000231 |
| GSE24585 | Down | -0.0344667123 |
| GSE37065 | Up | 0.0883250050 |
| GSE28863_A1 | Down | -0.1547175463 |
| GSE28863_A2 | Down | -0.0180986742 |
| GSE28863_A3 | Up | 0.1403057810 |
| GSE28863_A4 | Up | 0.0100958994 |
| GSE48662 | Down | -0.0175568829 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017608 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-1 | MIMAT0000416 | MIRT023735 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028032 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
