HCSGD entry for TAOK3

1. General information

Official gene symbolTAOK3
Entrez ID51347
Gene full nameTAO kinase 3
Other gene symbolsDPK JIK MAP3K18
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000165MAPK cascadeIMPbiological_process
GO:0000186Activation of MAPKK activityIBAbiological_process
GO:0004672Protein kinase activityIEAmolecular_function
GO:0004674Protein serine/threonine kinase activityIDA IEAmolecular_function
GO:0004709MAP kinase kinase kinase activityIBAmolecular_function
GO:0004860Protein kinase inhibitor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005739MitochondrionIDAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0006281DNA repairIEAbiological_process
GO:0006468Protein phosphorylationIDA IMPbiological_process
GO:0006469Negative regulation of protein kinase activityTASbiological_process
GO:0006974Cellular response to DNA damage stimulusIDAbiological_process
GO:0016301Kinase activityIEAmolecular_function
GO:0016740Transferase activityIDAmolecular_function
GO:0031572G2 DNA damage checkpointIMPbiological_process
GO:0032874Positive regulation of stress-activated MAPK cascadeIMPbiological_process
GO:0043086Negative regulation of catalytic activityTASbiological_process
GO:0043507Positive regulation of JUN kinase activityIMPbiological_process
GO:0046329Negative regulation of JNK cascadeIDAbiological_process
GO:0046330Positive regulation of JNK cascadeIMPbiological_process
GO:0046777Protein autophosphorylationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.31507086740.41062233960.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1842260921
GSE13712_SHEARUp0.3216993956
GSE13712_STATICUp0.5099114184
GSE19018Up0.0189780261
GSE19899_A1Down-0.7481063991
GSE19899_A2Down-0.0892001698
PubMed_21979375_A1Down-0.4427054699
PubMed_21979375_A2Down-0.2621260668
GSE35957Up0.0191638164
GSE36640Up0.4136095746
GSE54402Down-0.1540428147
GSE9593Up0.3861704564
GSE43922Down-0.4935556394
GSE24585Up0.2115876312
GSE37065Up0.1114220000
GSE28863_A1Down-0.0311976306
GSE28863_A2Up0.4834845780
GSE28863_A3Down-0.3314388546
GSE28863_A4Up0.1683847566
GSE48662Down-0.1148747065

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-193b-3pMIMAT0002819MIRT041263CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.