HCSGD entry for SPTBN5
1. General information
| Official gene symbol | SPTBN5 |
|---|---|
| Entrez ID | 51332 |
| Gene full name | spectrin, beta, non-erythrocytic 5 |
| Other gene symbols | BSPECV HUBSPECV HUSPECV |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | NAS | molecular_function |
| GO:0005635 | Nuclear envelope | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0008091 | Spectrin | NAS | cellular_component |
| GO:0016020 | Membrane | NAS | cellular_component |
| GO:0030036 | Actin cytoskeleton organization | NAS | biological_process |
| GO:0040023 | Establishment of nucleus localization | IEA | biological_process |
| GO:0042803 | Protein homodimerization activity | IEA | molecular_function |
| GO:0051693 | Actin filament capping | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7605549789 | 0.3343953459 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2524575010 |
| GSE13712_SHEAR | Down | -0.6107839317 |
| GSE13712_STATIC | Down | -0.5908231064 |
| GSE19018 | Up | 0.1795241094 |
| GSE19899_A1 | Down | -0.1699080196 |
| GSE19899_A2 | Down | -0.0636816014 |
| PubMed_21979375_A1 | Up | 0.3518998015 |
| PubMed_21979375_A2 | Down | -0.0657357473 |
| GSE35957 | Up | 0.0548211881 |
| GSE36640 | Up | 0.1224629235 |
| GSE54402 | Down | -0.0606464310 |
| GSE9593 | Up | 0.3041164428 |
| GSE43922 | Up | 0.0583970816 |
| GSE24585 | Down | -0.0072504282 |
| GSE37065 | Down | -0.0116238867 |
| GSE28863_A1 | Down | -0.0188825255 |
| GSE28863_A2 | Down | -0.1407449927 |
| GSE28863_A3 | Up | 0.2346381303 |
| GSE28863_A4 | Up | 0.0184959405 |
| GSE48662 | Up | 0.0480007950 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018034 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-let-7f-5p | MIMAT0000067 | MIRT051390 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
