HCSGD entry for PDC
1. General information
| Official gene symbol | PDC |
|---|---|
| Entrez ID | 5132 |
| Gene full name | phosducin |
| Other gene symbols | MEKA PHD PhLOP PhLP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001750 | Photoreceptor outer segment | IEA | cellular_component |
| GO:0001917 | Photoreceptor inner segment | IEA | cellular_component |
| GO:0004859 | Phospholipase inhibitor activity | TAS | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007601 | Visual perception | IEA | biological_process |
| GO:0007602 | Phototransduction | TAS | biological_process |
| GO:0015629 | Actin cytoskeleton | IDA | cellular_component |
| GO:0043086 | Negative regulation of catalytic activity | TAS | biological_process |
| GO:0050790 | Regulation of catalytic activity | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5904904411 | 0.6199565708 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2740336302 |
| GSE13712_SHEAR | Down | -0.3223436883 |
| GSE13712_STATIC | Up | 0.0480298456 |
| GSE19018 | Down | -0.0240463174 |
| GSE19899_A1 | Up | 0.0472997221 |
| GSE19899_A2 | Up | 0.0205501976 |
| PubMed_21979375_A1 | Down | -0.0327369951 |
| PubMed_21979375_A2 | Down | -0.0593710022 |
| GSE35957 | Up | 0.2260076759 |
| GSE36640 | Up | 0.0841352655 |
| GSE54402 | Up | 0.4827726921 |
| GSE9593 | Down | -0.2492026178 |
| GSE43922 | Up | 0.0147879319 |
| GSE24585 | Down | -0.1176821325 |
| GSE37065 | Up | 0.1288470053 |
| GSE28863_A1 | Down | -0.0795449445 |
| GSE28863_A2 | Down | -0.0333229127 |
| GSE28863_A3 | Up | 0.0027362788 |
| GSE28863_A4 | Down | -0.0998901662 |
| GSE48662 | Down | -0.0841269740 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 26201620 | Environmental triggers appear to disrupt the pre-existing, unstable immune tolerance in genetically susceptible individuals, and molecular mimics of the PBC-specific autoantigen (PDC) may be derived from microbes or xenobiotic compounds, which modify native proteins, making them immunogenic |
Entries Per Page
Displaying Page of
