HCSGD entry for GMIP


1. General information

Official gene symbolGMIP
Entrez ID51291
Gene full nameGEM interacting protein
Other gene symbolsARHGAP46
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005100Rho GTPase activator activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularIC IEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0032320Positive regulation of Ras GTPase activityIDAbiological_process
GO:0032321Positive regulation of Rho GTPase activityIDAbiological_process
GO:0034259Negative regulation of Rho GTPase activityIDAbiological_process
GO:0035556Intracellular signal transductionIDA IEAbiological_process
GO:0043085Positive regulation of catalytic activityIDAbiological_process
GO:0043547Positive regulation of GTPase activityIDAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02230112080.98855246760.35726585511.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2081398755
GSE13712_SHEARUp0.2049844311
GSE13712_STATICUp0.5495306739
GSE19018Down-0.0766469753
GSE19899_A1Up0.2755562815
GSE19899_A2Up0.6134576608
PubMed_21979375_A1Up0.5337110403
PubMed_21979375_A2Up1.0318443362
GSE35957Up0.1650136080
GSE36640Up0.4797227186
GSE54402Up0.3089897503
GSE9593Up0.0282708427
GSE43922Up0.5240339233
GSE24585Up0.1834508751
GSE37065Up0.1399106736
GSE28863_A1Down-0.1395608498
GSE28863_A2Down-0.0784059466
GSE28863_A3Up0.0794117532
GSE28863_A4Up0.0738511733
GSE48662Up0.1089641944

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.