HCSGD entry for MARCH2
1. General information
| Official gene symbol | MARCH2 |
|---|---|
| Entrez ID | 51257 |
| Gene full name | membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase |
| Other gene symbols | MARCH-II RNF172 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005765 | Lysosomal membrane | IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0006897 | Endocytosis | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0010008 | Endosome membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016567 | Protein ubiquitination | IDA | biological_process |
| GO:0031410 | Cytoplasmic vesicle | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0141622659 | 0.4055186923 | 0.2944932965 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0103443894 |
| GSE13712_SHEAR | Up | 0.0291730234 |
| GSE13712_STATIC | Up | 0.6409213614 |
| GSE19018 | Up | 0.8367624229 |
| GSE19899_A1 | Down | -0.3761349262 |
| GSE19899_A2 | Up | 1.0087502909 |
| PubMed_21979375_A1 | Up | 0.2885252583 |
| PubMed_21979375_A2 | Up | 1.2847444252 |
| GSE35957 | Up | 0.0578160818 |
| GSE36640 | Up | 1.8315999386 |
| GSE54402 | Down | -0.5559578595 |
| GSE9593 | Up | 0.8981553883 |
| GSE43922 | Up | 0.0489515332 |
| GSE24585 | Up | 0.1878986831 |
| GSE37065 | Down | -0.0729828393 |
| GSE28863_A1 | Down | -0.5888106041 |
| GSE28863_A2 | Down | -0.0646512163 |
| GSE28863_A3 | Down | -0.3877371601 |
| GSE28863_A4 | Up | 0.0130927311 |
| GSE48662 | Up | 0.4421357049 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019377 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
