HCSGD entry for SHISA5


1. General information

Official gene symbolSHISA5
Entrez ID51246
Gene full nameshisa homolog 5 (Xenopus laevis)
Other gene symbolsSCOTIN
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004871Signal transducer activityIMPmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005635Nuclear envelopeIEAcellular_component
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0031965Nuclear membraneIEAcellular_component
GO:0042771Intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorIEAbiological_process
GO:0043123Positive regulation of I-kappaB kinase/NF-kappaB signalingIMPbiological_process
GO:0050699WW domain bindingIPImolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.05450647770.92849089700.50965008881.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4517465461
GSE13712_SHEARUp0.5757204751
GSE13712_STATICUp0.5622617629
GSE19018Up0.1873263225
GSE19899_A1Down-0.0673453147
GSE19899_A2Up0.7207882587
PubMed_21979375_A1Up0.1840687516
PubMed_21979375_A2Up0.9301050471
GSE35957Down-0.4375232251
GSE36640Up0.7092701895
GSE54402Down-0.4068302343
GSE9593Up0.0592294318
GSE43922Down-0.0150533987
GSE24585Up0.1069063552
GSE37065Up0.1487282876
GSE28863_A1Up0.1164960916
GSE28863_A2Up0.2470183877
GSE28863_A3Down-0.0365012918
GSE28863_A4Down-0.0847672907
GSE48662Up0.1673925152

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-7-5pMIMAT0000252MIRT025901MicroarrayFunctional MTI (Weak)19073608
hsa-miR-1296-5pMIMAT0005794MIRT036083CLASHFunctional MTI (Weak)23622248
hsa-miR-877-5pMIMAT0004949MIRT037247CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT048940CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.