HCSGD entry for PHF20
1. General information
| Official gene symbol | PHF20 |
|---|---|
| Entrez ID | 51230 |
| Gene full name | PHD finger protein 20 |
| Other gene symbols | C20orf104 GLEA2 HCA58 NZF TDRD20A TZP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000123 | Histone acetyltransferase complex | IDA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0031965 | Nuclear membrane | IDA | cellular_component |
| GO:0043981 | Histone H4-K5 acetylation | IDA | biological_process |
| GO:0043982 | Histone H4-K8 acetylation | IDA | biological_process |
| GO:0043984 | Histone H4-K16 acetylation | IDA | biological_process |
| GO:0043995 | Histone acetyltransferase activity (H4-K5 specific) | IDA | molecular_function |
| GO:0043996 | Histone acetyltransferase activity (H4-K8 specific) | IDA | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0046972 | Histone acetyltransferase activity (H4-K16 specific) | IDA | molecular_function |
| GO:0071339 | MLL1 complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7767534820 | 0.3910664754 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1566294906 |
| GSE13712_SHEAR | Up | 0.2355623471 |
| GSE13712_STATIC | Up | 0.1361852483 |
| GSE19018 | Up | 0.1734653997 |
| GSE19899_A1 | Down | -0.0960865673 |
| GSE19899_A2 | Up | 0.1074996722 |
| PubMed_21979375_A1 | Down | -0.3890454272 |
| PubMed_21979375_A2 | Down | -0.3940375935 |
| GSE35957 | Up | 0.0846193276 |
| GSE36640 | Down | -0.2211070667 |
| GSE54402 | Down | -0.1878460152 |
| GSE9593 | Up | 0.0707515865 |
| GSE43922 | Down | -0.1438839966 |
| GSE24585 | Up | 0.3797330616 |
| GSE37065 | Down | -0.0753602583 |
| GSE28863_A1 | Down | -0.0186434129 |
| GSE28863_A2 | Up | 0.0223849052 |
| GSE28863_A3 | Down | -0.1399889383 |
| GSE28863_A4 | Up | 0.0678604357 |
| GSE48662 | Up | 0.1289443893 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-197-3p | MIMAT0000227 | MIRT004205 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030969 | Microarray | Functional MTI (Weak) | 18591254 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 26868148 | Ectopic expression of a catalytic mutant of KDM4A stabilizes p53 and enhances p53 interaction with PHF20 in the presence of Fbxo22 |
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