HCSGD entry for CKLF


1. General information

Official gene symbolCKLF
Entrez ID51192
Gene full namechemokine-like factor
Other gene symbolsC32 CKLF1 CKLF2 CKLF3 CKLF4 UCK-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005576Extracellular regionIDAcellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0008009Chemokine activityIDAmolecular_function
GO:0008283Cell proliferationIDAbiological_process
GO:0016021Integral component of membraneIDAcellular_component
GO:0030593Neutrophil chemotaxisIDAbiological_process
GO:0032940Secretion by cellIDAbiological_process
GO:0048246Macrophage chemotaxisIDAbiological_process
GO:0048247Lymphocyte chemotaxisIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.92184519590.09640476810.99999024730.5918739039

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1476949597
GSE13712_SHEARUp0.1832584372
GSE13712_STATICUp0.0486946323
GSE19018Up0.3198695804
GSE19899_A1Up0.1732750655
GSE19899_A2Down-0.8061818676
PubMed_21979375_A1Down-1.0280857253
PubMed_21979375_A2Down-0.2578220728
GSE35957Down-0.7595074178
GSE36640Down-0.8436982444
GSE54402Up0.0467974158
GSE9593Down-0.3188673484
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.0783137207

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-148b-3pMIMAT0000759MIRT019431MicroarrayFunctional MTI (Weak)17612493
hsa-miR-215-5pMIMAT0000272MIRT024446MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026750MicroarrayFunctional MTI (Weak)19074876
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.