HCSGD entry for HSD17B11


1. General information

Official gene symbolHSD17B11
Entrez ID51170
Gene full namehydroxysteroid (17-beta) dehydrogenase 11
Other gene symbols17BHSD11 DHRS8 PAN1B RETSDR2 SDR16C2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004303Estradiol 17-beta-dehydrogenase activityIEAmolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005811Lipid particleIDAcellular_component
GO:0006694Steroid biosynthetic processIEAbiological_process
GO:0006710Androgen catabolic processIDAbiological_process
GO:0016229Steroid dehydrogenase activityIDAmolecular_function
GO:0016491Oxidoreductase activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.95632051210.00118402420.99999024730.0651981172

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0990750557
GSE13712_SHEARDown-0.7030818489
GSE13712_STATICDown-0.5138488693
GSE19018Down-0.2193472404
GSE19899_A1Down-1.7323617635
GSE19899_A2Down-2.9300845640
PubMed_21979375_A1Down-1.8442490485
PubMed_21979375_A2Down-2.8384120693
GSE35957Up0.1131696678
GSE36640Up0.3118437568
GSE54402Down-1.1276919667
GSE9593Down-0.1407781031
GSE43922Down-1.6156590319
GSE24585Up0.7759705649
GSE37065Down-0.0934561939
GSE28863_A1Up0.0765974923
GSE28863_A2Up0.0568081967
GSE28863_A3Down-0.5253583163
GSE28863_A4Down-0.2350983104
GSE48662Down-0.3197461735

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

AetiocholanoloneDB02854 EXPT00443

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT023862ProteomicsFunctional MTI (Weak)18668040
hsa-miR-26b-5pMIMAT0000083MIRT029679MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.