HCSGD entry for VPS28


1. General information

Official gene symbolVPS28
Entrez ID51160
Gene full namevacuolar protein sorting 28 homolog (S. cerevisiae)
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000813ESCRT I complexIDAcellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005768EndosomeIDAcellular_component
GO:0005829CytosolIDAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0010008Endosome membraneTAScellular_component
GO:0015031Protein transportIEAbiological_process
GO:0016032Viral processTASbiological_process
GO:0016197Endosomal transportTASbiological_process
GO:0019068Virion assemblyTASbiological_process
GO:0019082Viral protein processingTASbiological_process
GO:0031397Negative regulation of protein ubiquitinationIDAbiological_process
GO:0031902Late endosome membraneIEAcellular_component
GO:0043162Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathwayIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.62960411460.21343529120.99999024730.8922153565

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1678948192
GSE13712_SHEARDown-0.3731055764
GSE13712_STATICDown-0.3143976739
GSE19018Up0.4648260441
GSE19899_A1Down-0.3711098635
GSE19899_A2Down-0.0395320369
PubMed_21979375_A1Up1.6669630467
PubMed_21979375_A2Up0.0667931886
GSE35957Down-0.1056771545
GSE36640Up0.3835408883
GSE54402Up0.4243160221
GSE9593Down-0.0600959322
GSE43922Down-0.0157786834
GSE24585Down-0.2165486511
GSE37065Down-0.1400330868
GSE28863_A1Down-0.0970075309
GSE28863_A2Down-0.2278398767
GSE28863_A3Up0.0125908829
GSE28863_A4Down-0.0332457924
GSE48662Down-0.0882829603

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-328-3pMIMAT0000752MIRT043761CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT052309CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.