HCSGD entry for ANGPTL4
1. General information
| Official gene symbol | ANGPTL4 |
|---|---|
| Entrez ID | 51129 |
| Gene full name | angiopoietin-like 4 |
| Other gene symbols | ANGPTL2 ARP4 FIAF HFARP NL2 PGAR pp1158 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001525 | Angiogenesis | IEA | biological_process |
| GO:0001666 | Response to hypoxia | IEA NAS | biological_process |
| GO:0004857 | Enzyme inhibitor activity | IEA ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | IDA IEA TAS | cellular_component |
| GO:0005578 | Proteinaceous extracellular matrix | IEA | cellular_component |
| GO:0005615 | Extracellular space | IDA | cellular_component |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | IDA | biological_process |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045766 | Positive regulation of angiogenesis | TAS | biological_process |
| GO:0051005 | Negative regulation of lipoprotein lipase activity | IDA IEA | biological_process |
| GO:0051260 | Protein homooligomerization | IEA | biological_process |
| GO:0070328 | Triglyceride homeostasis | IEA ISS | biological_process |
| GO:2000352 | Negative regulation of endothelial cell apoptotic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0000262262 | 0.9813275901 | 0.0149063830 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0642670439 |
| GSE13712_SHEAR | Up | 0.5793208312 |
| GSE13712_STATIC | Up | 1.6702060595 |
| GSE19018 | Up | 0.0903931268 |
| GSE19899_A1 | Up | 1.8622281818 |
| GSE19899_A2 | Up | 5.5134786661 |
| PubMed_21979375_A1 | Up | 3.0096185446 |
| PubMed_21979375_A2 | Up | 5.5475227927 |
| GSE35957 | Down | -0.3730085412 |
| GSE36640 | Up | 1.3747437121 |
| GSE54402 | Up | 1.8207152602 |
| GSE9593 | Up | 0.3992597938 |
| GSE43922 | Up | 3.5579537050 |
| GSE24585 | Down | -0.0851425640 |
| GSE37065 | Up | 0.8482235622 |
| GSE28863_A1 | Down | -0.1423325441 |
| GSE28863_A2 | Up | 0.5494497607 |
| GSE28863_A3 | Up | 0.2646457388 |
| GSE28863_A4 | Down | -0.1560742068 |
| GSE48662 | Up | 1.5087096160 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022740 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT023828 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
