HCSGD entry for SBDS
1. General information
| Official gene symbol | SBDS |
|---|---|
| Entrez ID | 51119 |
| Gene full name | Shwachman-Bodian-Diamond syndrome |
| Other gene symbols | SDS SWDS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000922 | Spindle pole | IDA | cellular_component |
| GO:0001833 | Inner cell mass cell proliferation | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006364 | RRNA processing | IMP | biological_process |
| GO:0008017 | Microtubule binding | IDA | molecular_function |
| GO:0008283 | Cell proliferation | IMP | biological_process |
| GO:0019843 | RRNA binding | IDA | molecular_function |
| GO:0030282 | Bone mineralization | IMP | biological_process |
| GO:0030595 | Leukocyte chemotaxis | IDA | biological_process |
| GO:0042256 | Mature ribosome assembly | IDA | biological_process |
| GO:0042273 | Ribosomal large subunit biogenesis | IBA | biological_process |
| GO:0043022 | Ribosome binding | IDA | molecular_function |
| GO:0043148 | Mitotic spindle stabilization | IDA | biological_process |
| GO:0048539 | Bone marrow development | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2631806276 | 0.9904985183 | 0.9571355070 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | - | - |
| GSE13712_SHEAR | - | - |
| GSE13712_STATIC | - | - |
| GSE19018 | - | - |
| GSE19899_A1 | - | - |
| GSE19899_A2 | - | - |
| PubMed_21979375_A1 | - | - |
| PubMed_21979375_A2 | - | - |
| GSE35957 | - | - |
| GSE36640 | - | - |
| GSE54402 | - | - |
| GSE9593 | - | - |
| GSE43922 | Up | 0.0838223879 |
| GSE24585 | Up | 0.1052403352 |
| GSE37065 | Down | -0.0083314092 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.2307309206 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-590-3p | MIMAT0004801 | MIRT016171 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051786 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 23231002 | RESULTS: Intense granular expression of PDC-E2 and CCO was seen in the damaged small bile ducts (SBDs) in PBC and the expression was significantly more frequent in PBC than in control livers (P < 0 |
| 23231002 | The granular expression of mitochondrial antigens was colocalized with LC3 in damaged SBDs in PBC |
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