HCSGD entry for ABHD5
1. General information
| Official gene symbol | ABHD5 |
|---|---|
| Entrez ID | 51099 |
| Gene full name | abhydrolase domain containing 5 |
| Other gene symbols | CDS CGI58 IECN2 NCIE2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity | IEA | molecular_function |
| GO:0004806 | Triglyceride lipase activity | ISS | molecular_function |
| GO:0005811 | Lipid particle | IDA IEA ISS | cellular_component |
| GO:0005829 | Cytosol | IEA ISS | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0006629 | Lipid metabolic process | IEA | biological_process |
| GO:0006631 | Fatty acid metabolic process | IEA | biological_process |
| GO:0006654 | Phosphatidic acid biosynthetic process | IDA | biological_process |
| GO:0008233 | Peptidase activity | IEA | molecular_function |
| GO:0010891 | Negative regulation of sequestering of triglyceride | IDA IEA | biological_process |
| GO:0010898 | Positive regulation of triglyceride catabolic process | IDA IEA | biological_process |
| GO:0019433 | Triglyceride catabolic process | TAS | biological_process |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0042171 | Lysophosphatidic acid acyltransferase activity | IDA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0051006 | Positive regulation of lipoprotein lipase activity | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0077749136 | 0.9473726872 | 0.2284627232 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3012553561 |
| GSE13712_SHEAR | Up | 0.6887989973 |
| GSE13712_STATIC | Up | 0.8999253763 |
| GSE19018 | Down | -0.5482048530 |
| GSE19899_A1 | Up | 0.5301346801 |
| GSE19899_A2 | Up | 0.0762338643 |
| PubMed_21979375_A1 | Up | 0.6911018066 |
| PubMed_21979375_A2 | Up | 1.3947800697 |
| GSE35957 | Up | 0.6330947412 |
| GSE36640 | Up | 0.1035328545 |
| GSE54402 | Down | -0.0171300459 |
| GSE9593 | Up | 0.0136912206 |
| GSE43922 | Up | 0.3606941705 |
| GSE24585 | Up | 0.6020527837 |
| GSE37065 | Up | 0.0417332632 |
| GSE28863_A1 | Up | 0.3726621629 |
| GSE28863_A2 | Up | 0.5888264607 |
| GSE28863_A3 | Down | -0.1707344622 |
| GSE28863_A4 | Down | -0.2460491252 |
| GSE48662 | Down | -0.3602440996 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002698 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002698 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031166 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
