HCSGD entry for POLR1D
1. General information
| Official gene symbol | POLR1D |
|---|---|
| Entrez ID | 51082 |
| Gene full name | polymerase (RNA) I polypeptide D, 16kDa |
| Other gene symbols | AC19 POLR1C RPA16 RPA9 RPAC2 RPC16 RPO1-3 TCS2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001054 | RNA polymerase I activity | IBA | molecular_function |
| GO:0001056 | RNA polymerase III activity | IBA | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005666 | DNA-directed RNA polymerase III complex | IBA | cellular_component |
| GO:0005736 | DNA-directed RNA polymerase I complex | IBA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006360 | Transcription from RNA polymerase I promoter | TAS | biological_process |
| GO:0006361 | Transcription initiation from RNA polymerase I promoter | TAS | biological_process |
| GO:0006362 | Transcription elongation from RNA polymerase I promoter | TAS | biological_process |
| GO:0006363 | Termination of RNA polymerase I transcription | TAS | biological_process |
| GO:0006383 | Transcription from RNA polymerase III promoter | TAS | biological_process |
| GO:0006385 | Transcription elongation from RNA polymerase III promoter | TAS | biological_process |
| GO:0006386 | Termination of RNA polymerase III transcription | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0032481 | Positive regulation of type I interferon production | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0046983 | Protein dimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4661369895 | 0.3378864519 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0419539779 |
| GSE13712_SHEAR | Down | -0.3103964889 |
| GSE13712_STATIC | Down | -0.1580389497 |
| GSE19018 | Up | 0.2230629755 |
| GSE19899_A1 | Up | 0.3682150592 |
| GSE19899_A2 | Up | 0.5998786801 |
| PubMed_21979375_A1 | Up | 0.5302986912 |
| PubMed_21979375_A2 | Up | 0.2604200264 |
| GSE35957 | Down | -0.4090330132 |
| GSE36640 | Down | -0.2583083932 |
| GSE54402 | Up | 0.3153486969 |
| GSE9593 | Up | 0.1742731163 |
| GSE43922 | Up | 0.0002600774 |
| GSE24585 | Down | -0.1736937539 |
| GSE37065 | Down | -0.3166119933 |
| GSE28863_A1 | Up | 0.0215766189 |
| GSE28863_A2 | Down | -0.3953723460 |
| GSE28863_A3 | Down | -0.2567850543 |
| GSE28863_A4 | Up | 0.0385969798 |
| GSE48662 | Down | -0.2001601062 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027718 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-374a-3p | MIMAT0004688 | MIRT038262 | CLASH | Functional MTI (Weak) | 23622248 |
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