HCSGD entry for PCM1

1. General information

Official gene symbolPCM1
Entrez ID5108
Gene full namepericentriolar material 1
Other gene symbolsPTC4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000086G2/M transition of mitotic cell cycleTASbiological_process
GO:0000242Pericentriolar materialIEA ISScellular_component
GO:0000278Mitotic cell cycleTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDA ISScellular_component
GO:0005813CentrosomeIDA ISScellular_component
GO:0005829CytosolTAScellular_component
GO:0022027Interkinetic nuclear migrationIEA ISSbiological_process
GO:0031513Nonmotile primary ciliumIDAcellular_component
GO:0031965Nuclear membraneIDAcellular_component
GO:0034451Centriolar satelliteIDA IEAcellular_component
GO:0034453Microtubule anchoringISSbiological_process
GO:0034454Microtubule anchoring at centrosomeIEAbiological_process
GO:0042384Cilium assemblyIMPbiological_process
GO:0042802Identical protein bindingISSmolecular_function
GO:0050768Negative regulation of neurogenesisIEA ISSbiological_process
GO:0051297Centrosome organizationIMPbiological_process
GO:0071539Protein localization to centrosomeIEA ISSbiological_process
GO:0097150Neuronal stem cell maintenanceIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.13471777670.41006940470.74333895971.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0711080393
GSE13712_SHEARDown-0.1373241935
GSE13712_STATICDown-0.1140644378
GSE19018Up0.2632030880
GSE19899_A1Up0.0830394433
GSE19899_A2Down-0.3057383515
PubMed_21979375_A1Down-0.4421528006
PubMed_21979375_A2Up0.0085625370
GSE35957Up0.0148076032
GSE36640Down-0.6591394068
GSE54402Down-0.2423214076
GSE9593Up0.1255512859
GSE43922Down-0.0093402744
GSE24585Up0.2593080631
GSE37065Down-0.0035386846
GSE28863_A1Up1.5589023656
GSE28863_A2Up1.4978609503
GSE28863_A3Down-0.1535309506
GSE28863_A4Down-0.1763824737
GSE48662Down-0.1498036769

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-33a-5pMIMAT0000091MIRT049852CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.