HCSGD entry for ATL1
1. General information
| Official gene symbol | ATL1 |
|---|---|
| Entrez ID | 51062 |
| Gene full name | atlastin GTPase 1 |
| Other gene symbols | AD-FSP FSP1 GBP3 HSN1D SPG3 SPG3A atlastin1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000137 | Golgi cis cisterna | IEA ISS | cellular_component |
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0003924 | GTPase activity | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA ISS | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA ISS | cellular_component |
| GO:0005794 | Golgi apparatus | ISS | cellular_component |
| GO:0006184 | GTP catabolic process | IDA | biological_process |
| GO:0007029 | Endoplasmic reticulum organization | IDA | biological_process |
| GO:0007409 | Axonogenesis | IEA ISS | biological_process |
| GO:0008152 | Metabolic process | IDA | biological_process |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IDA | cellular_component |
| GO:0030424 | Axon | IEA | cellular_component |
| GO:0042802 | Identical protein binding | IDA | molecular_function |
| GO:0051260 | Protein homooligomerization | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6055367539 | 0.0122490179 | 0.9999902473 | 0.2183796209 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0421916604 |
| GSE13712_SHEAR | Down | -0.1957416970 |
| GSE13712_STATIC | Up | 0.7334882283 |
| GSE19018 | Up | 0.1540622649 |
| GSE19899_A1 | Down | -1.4954240125 |
| GSE19899_A2 | Down | -1.0363557198 |
| PubMed_21979375_A1 | Down | -1.2449619748 |
| PubMed_21979375_A2 | Down | -1.1940317297 |
| GSE35957 | Down | -1.2150432834 |
| GSE36640 | Up | 0.5013730021 |
| GSE54402 | Down | -0.9746658794 |
| GSE9593 | Up | 0.7221653391 |
| GSE43922 | Down | -0.6513281915 |
| GSE24585 | Up | 0.1936221531 |
| GSE37065 | Up | 0.0511696090 |
| GSE28863_A1 | Down | -0.3887477072 |
| GSE28863_A2 | Up | 0.2544538070 |
| GSE28863_A3 | Down | -0.5217468568 |
| GSE28863_A4 | Up | 0.1831865810 |
| GSE48662 | Up | 0.0320578499 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018361 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-9-5p | MIMAT0000441 | MIRT021430 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-let-7f-5p | MIMAT0000067 | MIRT051409 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | NA | hsa-miR-373 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
