HCSGD entry for LAP3
1. General information
| Official gene symbol | LAP3 |
|---|---|
| Entrez ID | 51056 |
| Gene full name | leucine aminopeptidase 3 |
| Other gene symbols | LAP LAPEP PEPS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004177 | Aminopeptidase activity | IEA NAS | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005802 | Trans-Golgi network | IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA NAS | biological_process |
| GO:0008235 | Metalloexopeptidase activity | IEA NAS | molecular_function |
| GO:0019538 | Protein metabolic process | IEA | biological_process |
| GO:0030145 | Manganese ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0404846016 | 0.5609370769 | 0.4509501481 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5754748631 |
| GSE13712_SHEAR | Up | 0.5996315623 |
| GSE13712_STATIC | Up | 0.3543249074 |
| GSE19018 | Down | -0.8635401864 |
| GSE19899_A1 | Up | 0.4972393945 |
| GSE19899_A2 | Up | 0.1481374224 |
| PubMed_21979375_A1 | Down | -0.2048465000 |
| PubMed_21979375_A2 | Up | 0.0431920067 |
| GSE35957 | Down | -0.6511893072 |
| GSE36640 | Up | 0.7064292115 |
| GSE54402 | Up | 0.6148871950 |
| GSE9593 | Up | 0.2271660243 |
| GSE43922 | Up | 0.0559650793 |
| GSE24585 | Down | -0.0056064986 |
| GSE37065 | Up | 0.4799776543 |
| GSE28863_A1 | Up | 0.1004739218 |
| GSE28863_A2 | Up | 0.3398638062 |
| GSE28863_A3 | Down | -0.0618150499 |
| GSE28863_A4 | Up | 0.0126680862 |
| GSE48662 | Down | -0.7719944344 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Leucine Phosphonic Acid | DB02386 | EXPT02610 |
| (2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acid | DB07448 | - |
| L-PROLINE, 1-[(2S)-3-MERCAPTO-2-METHYL-1-OXOPROPYL]-4-(PHENYLTHIO)-, 4S | DB08766 | - |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
