HCSGD entry for ZNF593


1. General information

Official gene symbolZNF593
Entrez ID51042
Gene full namezinc finger protein 593
Other gene symbolsZT86
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0003714Transcription corepressor activityTASmolecular_function
GO:0005730NucleolusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01694731200.31972012840.32137622481.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.6143008260
GSE13712_SHEARUp0.7123974836
GSE13712_STATICUp0.9281120088
GSE19018Down-0.9734102291
GSE19899_A1Down-0.0128825531
GSE19899_A2Up1.1482486822
PubMed_21979375_A1Up2.1608163236
PubMed_21979375_A2Up1.6762157921
GSE35957Down-1.0875826187
GSE36640Down-0.1689317505
GSE54402Up0.5397586240
GSE9593Down-0.4009259113
GSE43922Up0.4568140047
GSE24585Down-0.2402038376
GSE37065Up0.0122491892
GSE28863_A1Down-0.1422149032
GSE28863_A2Down-0.0469384907
GSE28863_A3Down-0.1290026380
GSE28863_A4Down-0.1421402937
GSE48662Down-0.0574658874

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-877-3pMIMAT0004950MIRT037146CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.