HCSGD entry for GLRX2

1. General information

Official gene symbolGLRX2
Entrez ID51022
Gene full nameglutaredoxin 2
Other gene symbolsCGI-133 GRX2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003756Protein disulfide isomerase activityTASmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005739MitochondrionIDAcellular_component
GO:0006355Regulation of transcription, DNA-templatedNASbiological_process
GO:0006457Protein foldingTASbiological_process
GO:0006749Glutathione metabolic processTASbiological_process
GO:0006915Apoptotic processNASbiological_process
GO:0008794Arsenate reductase (glutaredoxin) activityTASmolecular_function
GO:0009055Electron carrier activityNASmolecular_function
GO:0009266Response to temperature stimulusNASbiological_process
GO:0009966Regulation of signal transductionNASbiological_process
GO:0010033Response to organic substanceIDAbiological_process
GO:0015035Protein disulfide oxidoreductase activityIEAmolecular_function
GO:0015038Glutathione disulfide oxidoreductase activityTASmolecular_function
GO:0030154Cell differentiationNASbiological_process
GO:0042262DNA protectionNASbiological_process
GO:0042542Response to hydrogen peroxideIDAbiological_process
GO:0045454Cell redox homeostasisTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:00515372 iron, 2 sulfur cluster bindingIEAmolecular_function
GO:0051775Response to redox stateTASbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09030015960.50324754380.63229329611.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.8885426132
GSE13712_SHEARUp0.5015091710
GSE13712_STATICUp0.2833631290
GSE19018Up0.4450112860
GSE19899_A1Up0.2697753342
GSE19899_A2Up0.0058674381
PubMed_21979375_A1Up0.3515113705
PubMed_21979375_A2Down-0.0061330568
GSE35957Down-0.8254164112
GSE36640Down-0.6137927459
GSE54402Up0.5357281226
GSE9593Down-0.1871686770
GSE43922Up0.1383460647
GSE24585Down-0.1087228878
GSE37065Up0.0518177141
GSE28863_A1Down-0.4449850044
GSE28863_A2Up0.0978427240
GSE28863_A3Down-0.0712195609
GSE28863_A4Down-0.0923854881
GSE48662Down-0.0984526385

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

GlutathioneDB00143 NUTR00029 | EXPT01650

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT030287MicroarrayFunctional MTI (Weak)19088304
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.