HCSGD entry for PCCB
1. General information
| Official gene symbol | PCCB |
|---|---|
| Entrez ID | 5096 |
| Gene full name | propionyl CoA carboxylase, beta polypeptide |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003989 | Acetyl-CoA carboxylase activity | IEA | molecular_function |
| GO:0004658 | Propionyl-CoA carboxylase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | TAS | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006633 | Fatty acid biosynthetic process | IEA | biological_process |
| GO:0006635 | Fatty acid beta-oxidation | TAS | biological_process |
| GO:0006766 | Vitamin metabolic process | TAS | biological_process |
| GO:0006767 | Water-soluble vitamin metabolic process | TAS | biological_process |
| GO:0006768 | Biotin metabolic process | TAS | biological_process |
| GO:0009317 | Acetyl-CoA carboxylase complex | IEA | cellular_component |
| GO:0016874 | Ligase activity | IEA | molecular_function |
| GO:0019626 | Short-chain fatty acid catabolic process | TAS | biological_process |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7528725998 | 0.1901132632 | 0.9999902473 | 0.8452930248 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1386227588 |
| GSE13712_SHEAR | Up | 0.3567833669 |
| GSE13712_STATIC | Up | 0.4794208763 |
| GSE19018 | Up | 0.1502804120 |
| GSE19899_A1 | Up | 0.0645500088 |
| GSE19899_A2 | Up | 0.2324776121 |
| PubMed_21979375_A1 | Up | 0.3173419491 |
| PubMed_21979375_A2 | Up | 0.4425520142 |
| GSE35957 | Down | -0.3226172963 |
| GSE36640 | Down | -0.0971355989 |
| GSE54402 | Up | 0.0645232737 |
| GSE9593 | Down | -0.2138192771 |
| GSE43922 | Down | -0.0155646925 |
| GSE24585 | Down | -0.0609834664 |
| GSE37065 | Down | -0.3242365393 |
| GSE28863_A1 | Up | 0.0128110610 |
| GSE28863_A2 | Down | -0.2271447061 |
| GSE28863_A3 | Down | -0.4490189783 |
| GSE28863_A4 | Down | -0.2537377134 |
| GSE48662 | Down | -0.4007986335 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Valine | DB00161 | NUTR00060 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020658 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029293 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032255 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039868 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043905 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
